Angioid streaks are irregular tracts emanating from a ring of peripapillary atrophy, believed to be irregular ruptures of Bruch’s membrane. They are associated with atrophic degeneration of the retinal pigment epithelium and rupture or absence of the choriocapillaris. The most frequent complication that threatens visual acuity is the development of choroidal neovascularization in the macular region, although most patients remain asymptomatic. Angioid streaks can be associated with systemic diseases in more than 50% of cases, such as pseudoxanthoma elasticum, Paget’s disease, beta-thalassemia, sickle cell anemia, Ehlers-Danlos syndrome, among others. It is an uncommon pathology, and timely diagnosis is important, primarily in patients with family history, as well as the prevention of trauma given the potential ophthalmological complications that may arise, such as subretinal hemorrhages due to the fragility of Bruch’s membrane, as changes occur in its ultrastructure; specifically in the intermediate elastic layer and the collagenous layer.