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Vitreoretinal Lymphoma

Wide-field color retinography showing extensive infiltration of yellowish subretinal material

OCT shows the material at different levels: sub-RPE, subretinal, and as a hyperreflective column extending to the innermost layers of the retina.

Description

Vitreoretinal lymphoma: primarily central nervous system lymphoma (CNSL) with ocular involvement, is a rare type of cancer that affects the vitreous and retina. It usually occurs in older adults and may be associated with central nervous system lymphoma. Symptoms include decreased vision, floaters, and photopsias, often misdiagnosed as uveitis due to its clinical presentation.

Comments

After 2 years of treatment for vitreoretinal lymphoma, this patient eventually developed lymphoma in the CNS.

Indication

65-year-old male, diagnosed with vitreoretinal lymphoma without initial involvement of the central nervous system (CNS).