Submacular hemorrhage is one of the complications of neovascular age-related macular degeneration. This hemorrhage can damage photoreceptors early, so it is important to perform a treatment preferably to displace the hemorrhage outside the macular area. One of these treatments is pars plana vitrectomy with subretinal rTPA injection and air exchange up to 50-70% of the volume of the vitreous cavity, to displace the hemorrhage.